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Mural Oncology PLC
NASDAQ:MURA

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Mural Oncology PLC
NASDAQ:MURA
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Price: 2.04 USD Market Closed
Market Cap: $35.4m

EV/EBIT

0.2
Current
63%
Cheaper
vs 3-y average of 0.6

Enterprise Value to EBIT (EV/EBIT) ratio compares a company`s total enterprise value to its earnings before interest and taxes. It shows how much investors are paying for each dollar of the company`s earnings, including both equity and debt.

EV/EBIT
0.2
=
Enterprise Value
$-23.5m
/
EBIT
$-105.6m

Enterprise Value to EBIT (EV/EBIT) ratio compares a company`s total enterprise value to its earnings before interest and taxes. It shows how much investors are paying for each dollar of the company`s earnings, including both equity and debt.

EV/EBIT
0.2
=
Enterprise Value
$-23.5m
/
EBIT
$-105.6m

Valuation Scenarios

Mural Oncology PLC is trading below its 3-year average

If EV/EBIT returns to its 3-Year Average (0.6), the stock would be worth $5.54 (172% upside from current price).

Statistics
Positive Scenarios
4/4
Maximum Downside
No Downside Scenarios
Maximum Upside
+5 900%
Average Upside
2 821%
Scenario EV/EBIT Value Implied Price Upside/Downside
Current Multiple 0.2 $2.04
0%
3-Year Average 0.6 $5.54
+172%
5-Year Average 0.6 $5.54
+172%
Industry Average 11.5 $104.85
+5 040%
Country Average 13.4 $122.41
+5 900%

Forward EV/EBIT
Today’s price vs future ebit

Today's Enterprise Value EBIT Forward EV/EBIT
$-23.5m
/
Oct 2025
$-105.6m
=
0.2
Current
$-23.5m
/
Dec 2025
$-103.5m
=
0.2
Forward
$-23.5m
/
Dec 2026
$-8.2m
=
2.9
Forward
$-23.5m
/
Dec 2027
$-3.1m
=
7.7
Forward

Forward EV/EBIT shows whether today’s EV/EBIT still looks high or low once future ebit are taken into account.

Peer Comparison

All Multiples
EV/EBIT
P/E
All Countries
Close
Market Cap EV/EBIT P/E
IE
Mural Oncology PLC
NASDAQ:MURA
35.3m USD 0.2 -0.3
FR
Pharnext SCA
OTC:PNEXF
6T USD -192 227.3 -160 127.7
US
Abbvie Inc
NYSE:ABBV
355.3B USD 19.7 84.9
US
Amgen Inc
NASDAQ:AMGN
187.9B USD 14.1 24.3
US
Gilead Sciences Inc
NASDAQ:GILD
165.8B USD 15.1 19.5
US
Vertex Pharmaceuticals Inc
NASDAQ:VRTX
110.5B USD 21.9 28
US
Epizyme Inc
F:EPE
94.1B EUR -565.5 -533.6
US
Regeneron Pharmaceuticals Inc
NASDAQ:REGN
81B USD 15.3 18
NL
argenx SE
XBRU:ARGX
42.4B EUR 42.4 38.4
US
Seagen Inc
F:SGT
39.3B EUR -60.1 -61.8
AU
CSL Ltd
ASX:CSL
62.2B AUD 13.2 30.9
EV/EBIT Multiple
EBIT Growth EV/EBIT to Growth
IE
M
Mural Oncology PLC
NASDAQ:MURA
Average EV/EBIT: 17.7
0.2
N/A N/A
FR
Pharnext SCA
OTC:PNEXF
Negative Multiple: -192 227.3 N/A N/A
US
Abbvie Inc
NYSE:ABBV
19.7
23%
0.9
US
Amgen Inc
NASDAQ:AMGN
14.1
3%
4.7
US
Gilead Sciences Inc
NASDAQ:GILD
15.1
13%
1.2
US
Vertex Pharmaceuticals Inc
NASDAQ:VRTX
21.9
17%
1.3
US
E
Epizyme Inc
F:EPE
Negative Multiple: -565.5 N/A N/A
US
Regeneron Pharmaceuticals Inc
NASDAQ:REGN
15.3
23%
0.7
NL
argenx SE
XBRU:ARGX
42.4
51%
0.8
US
S
Seagen Inc
F:SGT
Negative Multiple: -60.1 N/A N/A
AU
CSL Ltd
ASX:CSL
13.2
10%
1.3
P/E Multiple
Earnings Growth PEG
IE
M
Mural Oncology PLC
NASDAQ:MURA
Average P/E: 34.8
Negative Multiple: -0.3
N/A N/A
FR
Pharnext SCA
OTC:PNEXF
Negative Multiple: -160 127.7 N/A N/A
US
Abbvie Inc
NYSE:ABBV
84.9
97%
0.9
US
Amgen Inc
NASDAQ:AMGN
24.3
20%
1.2
US
Gilead Sciences Inc
NASDAQ:GILD
19.5
16%
1.2
US
Vertex Pharmaceuticals Inc
NASDAQ:VRTX
28
19%
1.5
US
E
Epizyme Inc
F:EPE
Negative Multiple: -533.6 N/A N/A
US
Regeneron Pharmaceuticals Inc
NASDAQ:REGN
18
14%
1.3
NL
argenx SE
XBRU:ARGX
38.4
30%
1.3
US
S
Seagen Inc
F:SGT
Negative Multiple: -61.8 N/A N/A
AU
CSL Ltd
ASX:CSL
30.9
9%
3.4

Market Distribution

Lower than 80% of companies in Ireland
Percentile
20th
Based on 222 companies
20th percentile
0.2
Low
0 — 8.1
Typical Range
8.1 — 17.2
High
17.2 —
Distribution Statistics
Ireland
Min 0
30th Percentile 8.1
Median 13.4
70th Percentile 17.2
Max 849.2

Mural Oncology PLC
Glance View

Market Cap
35.4m USD
Industry
Biotechnology

Mural Oncology PLC is a IE-based company operating in Biotechnology industry. Mural Oncology plc is a clinical-stage oncology company. The firm is leveraging its protein engineering platform to develop cytokine-based immunotherapies for the treatment of cancer. The company leverages its expertise in cytokine biology, immune cell modulation and protein engineering capabilities to develop immunotherapies. The firm is developing a portfolio of programs to broaden the potential and reach of cytokine-based immunotherapies for the treatment of cancers, particularly those with limited treatment options available. Its portfolio of programs includes Nemvaleukin alfa (Nemvaleukin)-IL-2, IL-12, and IL-18. Nemvaleukin is an engineered interleukin-2 (IL-2) variant designed to harness the potent anti-cancer capabilities of high-dose rhIL-2 while minimizing toxicity by selectively activating cancer-fighting CD8 T cells and NK cells. The tumor-targeted split IL-12 program focuses on delivering the therapeutic potential of IL-12 by splitting it into inactive component.

MURA Intrinsic Value
8.33 USD
Undervaluation 76%
Intrinsic Value
Price $2.04
M
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